RNA-cleaving Fluorescent DNAzymes (RFDs)

RFDs are DNA sequences that induce a cleavage (cutting) reaction in a substrate strand in response to the presence of a target. In this project, we at saiwa team segmented and measured regions of interest (the dots that constitute the microarray) relative to the background in printed RFD images. Printed microarrays can be used to test for the presence of specific targets (i.e., bacteria). We used around 100 RFD images that were provided by Didar Lab., McMaster uni.
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